Biological Activity of Isoflavonoids from Azorella madreporica
نویسندگان
چکیده
منابع مشابه
Yaretol, a norditerpenoid from Azorella madreporica.
A new norditerpenoid, yaretol (1), was isolated from the whole plant of Azorella madreporica. The structure of 1 was established by one- and two-dimensional NMR techniques and confirmed by X-ray diffraction analysis.
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The antioxidant activities of 24 isoflavonoids that were previously isolated as pure compounds from Dalbergia parviflora were evaluated using three different in vitro antioxidant-based assay systems: xanthine/xanthine oxidase (X/XO), ORAC, and DPPH. The isolates consisted of three subgroups, namely isoflavones, isoflavanones, and isoflavans, each of which appeared to have diversified substituen...
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Structures of three antioxidant isoflavonoids isolated from the cultured broth of Streptomyces sp. OH-1049 were shown to be 4',7,8-trihydroxyisoflavone (1), 3',4',7-trihydroxyisoflavone (2) and 8-chloro-3',4',5,7-tetrahydroxyisoflavone (3), respectively. Among them, 3 is a novel isoflavonoid possessing a chlorine atom in the molecule. Compound 1 was synthesized and its antitumor activities were...
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Seventeen isoflavonoids from isoflavone, isoflavanone and isoflavan classes are selected from Dalbergia parviflora. The ChEMBL database is representative from these molecules, most of which result highly drug-like. Binary rules appear risky for the selection of compounds with high antioxidant capacity in complementary xanthine/xanthine oxidase, ORAC, and DPPH model assays. Isoflavonoid structur...
متن کاملIsolation of isoflavonoids possessing antioxidant activity from the fermentation broth of Streptomyces sp.
Three antioxidant isoflavonoids characterized as 4',7,8-trihydroxyisoflavone (1), 3',4',7-trihydroxyisoflavone (2) and 8-chloro-3',4',5,7-tetrahydroxyisoflavone (3) were isolated from the cultured broth of Streptomyces sp. OH-1049. Among them, 3 is a novel isoflavonoid possessing a chlorine atom in the molecule. In in vitro studies, these antibiotics were found to possess antioxidant activity w...
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ژورنال
عنوان ژورنال: Natural Product Communications
سال: 2012
ISSN: 1934-578X,1555-9475
DOI: 10.1177/1934578x1200700921